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Top Biotech Startup in Europe

Top 10 Biotech Startup in Europe - 2021

It is a common belief that Biotechnology—the intersection of medicine, science, and technology—drives ways to pushing the limits of human lifespan. From data driven diagnostics to breakthrough gene therapies, Biotech is pivotal to the healthcare, agriculture and food industries. Consequently, these developments have led to soaring investments in this sector driving the rise of several innovative startups. The European Health and Biotech startups are now worth a combined value of $232B. Further, Biotech startups account for 79 percent of the European Healthcare and Biotech ecosystem, with European Biotechs worth a combined $184B in comparison to a collective value of $48B for European Healthtechs.

However, building a Biotech startup is quite complex in comparison to founding a SaaS startup and the funding processes can be different too. The Biotech startups are 1.5 times likely to raise a second round of investment than other startups. Although, as most companies mature, the round graduations rates tend to even out. In most cases, it requires greater amount of time and capital to prove validation for a potential cutting-edge Biotech solution.

Across majority European nations today, the newest Biotech entrants focus on several modalties including drug discovery tools and services, diagnostic and personalized care, CROs, and contract management organizations (CMOs). Besides, cell and gene therapies and immunotherapis are rapidly growing areas of treatments that are claiming more than forty percent of investment funding.

European Biotechs offer investors a lucrative space for growth and momentum with substantial opportunities that translate innovation into products. Armed with ample funding, the European market is on its way to attaining recognizable competitiveness and success in the upcoming years. On this note, Life Science Review has compiled its latest edition to shed light on the top-in-class Biotech startups in Europe to highlight the ones that can escalate the chances of your growth. This edition also offers a combination of thought leadership from subject-matter experts with real-life stories on fostering robust partnerships and exclusive insights from CIOs and CXOs.

We present to you, “Top 10 Biotech Startups in Europe - 2021.”

Top 10 Biotech Startup in Europe - 2021

Top Biotech Startup in Europe

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Elypta is a Swedish molecular diagnostics company focused on reducing cancer mortality through early detection and is pioneering a metabolism-based liquid biopsy and measures the GAGome – system biomarkers of tumour metabolism. The liquid biopsy platform is based on the discovery that panels of 17 metabolites - glycosaminoglycans (GAGs) - are specifically deregulated across several cancer types. The systems biology approach to identifying biomarkers is done by overlaying genome-wide data from cancer onto metabolic networks. Such an unbiased approach allows highlighting hot spots in metabolism unique to cancer, enabling the selection of a specific set of metabolites. ... read full profile

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EsoCap’s vision is to improve patients’ lives with serious illnesses by developing a unique topical drug delivery platform for diseases of the upper gastrointestinal tract. The organisation started as a biotech startup in Basel, Switzerland, has quickly grown into a pharmaceutical powerhouse led by a team with various educational backgrounds, skilled in multiple fields. EsoCap also collaborates with several external partners to carry out large scope operations. These external contributors include companies covering industrial development, the production of different drug delivery platform pieces, and scientific and regulatory advisors ... read full profile

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Spain-based Overture Life is a clinical-stage IVF automation company that is harnessing innovation to make reproductive technologies more consistent and affordable for healthcare professionals. It is revolutionising embryology by automating embryo testing, egg freezing, and embryo freezing to improve IVF pregnancy outcomes through process automation and non-invasive embryo selection. Making this possible is the company’s web-based, end-to-end, IVF-in-a-box solution — NaturaLife. Comprising multiple solutions that are awaiting FDA approval, NaturaLife aims to modernise IVF treatment via the holistic revamp of conventional embryology labs with a new, more intuitive, and consistent alternative where embryologists can follow a standardised approach to ensure embryo and egg viability before implantation. With NaturaLife’s process automation and non-invasive embryo selection, the company is also revolutionising embryo testing, egg freezing, and embryo freezing. ... read full profile

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Postbiotica has developed a novel, ex-vivo fermentation technology, PBTech, and brought it to an industrial level, ready for partnerships in B2B and licencing worldwide, as well as to bring to the market its brand. To facilitate this, Postbiotica has developed and industrialised an innovative fermentation technology, PBTech. This technology makes it possible to derive an array of postbiotics from selected microbial strains, not containing living or inanimate cells or any fragment of them. Since the PBTech technology does not rely on food fermentation, the final postbiotics no longer strictly follow the oral administration route. Rather, these compounds can be even administered through mucosal or ocular surfaces as well in a totally safe manner. This unique feature further expands the application of postbiotics developed by Postbiotica. ... read full profile

Arvelle Therapeutics

Arvelle Therapeutics is a Swiss-based company of the Angelini Pharma Group. They are dedicated to extending a helping hand to patients affected by CNS disorders. They implement innovative therapies and launch new CNS products to reach out to the patients. The company preserves a code of conduct to maintain right ethical standards and comply with the laws. The firm incorporates five core values to uphold their commitment to the patients. Integrity, accountability, rigorous analysis, collaboration and respect for the individual are the guiding principles of the code of conduct followed to grow their business.

BIT Pharma

BIT Pharma develops and commercializes technologies for site-specific drug delivery to the central nervous system (CNS), in particular the brain, exploiting tailored drug delivery systems. The company is developing NicaPlant® for patients affected by aneurysmal subarachnoid haemorrhage (aSAH), who are undergoing aneurysm closure by means of microsurgical application of a clip (clipping). The device is placed in close contact to the wall of cerebral arteries at the time of aneurysm clipping, in this way circumventing the blood brain barrier. The selection of the calcium channel blocker nicardipine, contained in NicaPlant® is based on its chemico-physical characteristics and on historical preclinical and clinical data in aSAH animal models and aSAH patients.

Formo

Formo is a food biotech company on a mission to bring the next generation of sustainable, healthy, and equitable dairy products to consumers. As an evolving diary they cultivate micro organisms and not cows. The company implements precision fermentation to create animal-free milk proteins and turn them into indulgent cheeses in the artisan tradition. Instructing, fermenting, harvesting, combining, coagulating and forming are the six scientific steps to make fresh and scrumptious cheese. The processes are all scientific yet in a traditional way.

Genomtec

Genomtec are the creators of Genomtec ID, a mobile platform for genetic diagnosis in the point of patient care. The company can boast of marketing the first SARS-CoV-2 rapid diagnostic kits including the world’s first genetic diagnostic test for the detection of SARS-CoV-2 directly from a saliva sample. Genomtec, founded by a group of scientists with experience and competences in the field of molecular biology, microstructures and photonics, has its headquarters and laboratories in Wrocław. It also has an office in the United Kingdom, where part of the international research and engineering team is located.

Lactobio

Lactobio focuses on the creation of new microbiome and microbial solutions to target and fight the problem of increasing infections caused by microorganisms being resistant to antibiotics. From nature to micro-based solutions, Lactobio is dedicated to research and new microbial solutions. A team of microbiologists, biotechnologists and biochemists identify, select and grow the best lactic acid bacterial strains to target microbiome dysfunctions associated with specific problems and diseases. State-of-the-art genomics and metabolomics are the techniques used to select the most effective strains. The discovery projects include different applications within skincare, human health, food and feed.

Nuvonis

Nuvonis is a biotech company providing innovative Cell Banks for vaccine and vector production that will dramatically speed up the development. Based in Vienna, the company provides technical support to vaccine development, both in small biotech companies up to major international pharmaceutical companies. An experienced team has identified several weak points in vaccine production. Cell line development, vaccine manufacturing, process optimization for vaccine or vector production and fast potency testing is the major area of focus. Nuvonis offers solutions that mitigate development timelines, ensure optimal quality and prevent risks in the product development.